The fibrinolytic mechanisms of streptokinase and reteplase are:
  1. Inhibit the formation of fibrin by disrupting the conversion of plasminogen to plasmin and activate the conversion of fibrin-bound plasminogen to plasmin respectively
  2. Both act directly on fibrin to dissolve it
  3. Both activate the conversion of fibrin-bound plasminogen to plasmin
  4. Both inhibit fibrin formation by disrupting the conversion of plasminogen to plasmin
Explanation
Answer: A - Specifically, streptokinase and reteplase cause fibrinolysis by disrupting the conversion of plasminogen to plasmin.
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