Respiratory Therapist

Category - Initiation and Modification of Interventions

Select all choices below that are true statements regarding mucolytic drugs
  1. The mucolytic drug, N-acetylcysteine disrupts sulfide bonds
  2. The mucolytic drug, sodium bicarbonate disrupts the sulfide bonds
  3. Mucolytics can be administered by aerosol or by direct instillation into the airway.
  4. The mucolytic, hypertonic saline is used to humidify inspired air and irritate the airway to promote a cough.
Explanation
Answers: A, B and C-N-acetylcysteine and sodium bicarbonate are both mucolytic drugs that disrupt sulfide bonds. Mucolytics can be administered via aerosol or by direct instillation to the airway.

Mucolytics are beneficial in treating patients with cystic fibrosis or those who have thick secretions they are unable to mobilize. Hypertonic saline is not a mucolytic drug, but it is used to humidify the inspired air and irritate the airway to promote a cough.
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