Polyhydramios is a complication of pregnancy in which there is an excessive amount of amniotic fluid (liquor amnii) surrounding the baby in the uterus. Which of the following is is not correlated to an increased risk of polyhydramnios?
  1. Anencephaly
  2. Spina bifida
  3. Diabetes
  4. Webbed toes
Explanation
Answer: D - Webbed toes

Polyhydramnios is the excessive accumulation of amniotic fluid surrounding the baby in the uterus, occuring in approximately 1% of pregnancies. Symptoms may include abdominal discomfort, increased back pain, shortness of breath, and swelling in feet and ankles. Causes include maternal diabetes, multiparity (e.g., twins), genetic abnormalities, fetal abnormalities, and fetal anemia. Some fetal anomalies correlated to a high risk of polyhydramnios include anencephaly, spina bifida, esophageal atresia, hydropsfetalis, chorioangioma.
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