A ten-year-old patient with a history of seizure disorder was admitted to the pediatric unit due to frequent seizure activity. The mother said that the child has been compliant with the medication (Phenytoin) therapy. Subsequently, a sample for the serum phenytoin level is drawn. The nurse determines that the medication has been most effective if the value is:
  1. 5 mcg/mL
  2. 12 mcg/mL
  3. 22 mcg/mL
  4. 30 mcg/mL
Explanation
Answer - B - The nurse determines that the medication has been most effective if the value is 12 mcg/mL. The therapeutic level for serum phynetoin is 10 - 20 mcg/mL. Seizure activity may continue if the level is below 10 mcg/mL. Toxicity may happen if the value is higher than 20 mcg/mL.
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