NCLEX-PN

Category - Pharmacological Therapies

A client with liver cirrhosis is admitted for fluid retention. Spironolactone (Aldactone) is prescribed by the physician. The nurse assigned to care for the client recognizes that the client is responding to the medication if which of the following assessment findings are noted?
  1. Weight loss of 2.5 pounds in 24 hours , K = 3.3 mEq/L
  2. Weight gain of 2.5 pounds in 24 hours, K = 4.8 mEq/L
  3. Weight loss of 2.5 pounds in 24 hours, K = 4.8 mEq/L
  4. Weight gain of 2.5 pounds in 24 hours, K = 3.3 mEq/L
Explanation
Answer: C - Spironolactone is a potassium-sparing diuretic commonly used to manage fluid retention in the absence of renal failure. Because it is a diuretic, the best indicator that the drug works is weight loss in 24 hours. Hypokalemia is not an expected finding because spironolactone is a potassium-sparing drug.
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