NCLEX-PN

Category - Pharmacological Therapies

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A client with active hallucinations and grandiose delusions is prescribed clozapine (Clozaril). The nurse expects the physician to order which laboratory test to monitor the adverse effects of the drug?

White blood cell count
Serum potassium
Platelet count
Serum sodium

Explanation

Answer: A - Agranulocytosis is the most severe adverse reaction caused by clozapine intake. This condition is manifested by significant decrease in the client’s WBC. A WBC count below 3000 cells/mm³ indicates the presence of agranulocytosis.

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