Podiatry and Medical - Set 1

Category - Podiatry Part I

Which of the following antitubercular agents is a strong inducer of hepatic cytochrome P450?
  1. Ethambutol
  2. Isoniazid
  3. Rifampin
  4. Streptomycin
Explanation
Answer − C − Rifampin is a strong inducer of hepatic cytochjrome P450 because it selectively inhibits bacterial DNA-dependent RNA polymerase. It is very useful in treating mycobacterial infections since it can penetrate cells and kill intracellular organisms.
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