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Podiatry and Medical - Set 1

Category - Podiatry Part I

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Which of the following antitubercular agents is a strong inducer of hepatic cytochrome P450?

Ethambutol
Isoniazid
Rifampin
Streptomycin

Explanation

Answer − C − Rifampin is a strong inducer of hepatic cytochjrome P450 because it selectively inhibits bacterial DNA-dependent RNA polymerase. It is very useful in treating mycobacterial infections since it can penetrate cells and kill intracellular organisms.

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