Podiatry and Medical - Set 1

Category - Podiatry Part I

Which of the following antifungal drugs is strongly associated with drug interactions resulting from inhibition of CYP 3A4?
  1. Amphotericin B
  2. Caspofungin
  3. Fluconazole
  4. Ketoconazole
Explanation
Answer − D − The antifungal drug that is strongly associated with drug interactions resulting from inhibition of CYP 3A is ketoconazole. Because CYP 3A4 is involved in the metabolism of almost 50% of the drugs in use, ketoconazole is implicated in many pharmacokinetic drug interactions.
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