PANCE Practice Test

Category - PA

Which of the following is required for vitamin B12 to be absorbed?
  1. A cyanide atom and form cyanocobalamin
  2. An intrinsic factor
  3. The parietal cells of the stomach
  4. The ileal mucosa
Explanation
Answer: B - Intrinsic factor is a glycoprotein that is secreted by the gastric parietal cells. In most people with vitamin B12 deficiency, the problem is inadequate production of intrinsic factor rather than inadequate vitamin B12 in the diet.
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