Emergency Medicine Test Prep

Category - Soft Tissue Trauma

During the inflammatory phase of wound healing The main function of the macrophages in wound healing is?
  1. removal of necrotic tissue
  2. removal of microorganisms
  3. production of cytokines
  4. all of the above
Explanation
Answer: D - first cells to move from the small vessels into the damaged tissue are polymorph nuclear, neutrophils (PMN) and macrophages. PMN are mobilized rapidly and produce an extremely vigorous initial response. The main function of the macrophages is the removal of necrotic tissue and microorganisms (phagocytosis and secretion of proteases) and the production and secretion of cytokines.
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