Clinical Nurse Specialist CNS Adult Practice Test

Category - AACN Clinical Nurse Specialist Practice Test

What class of drugs is recommended as the first line therapy for hypercholesterolemia, after lifestyle modifications?
  1. HMG-CoA reductase inhibitors (statins)
  2. Calcium channel blockers
  3. Beta channel antagonists
  4. Antithrombolytics
Explanation
Answer: A - The statins work by blocking an enzyme, HMG-CoA reductase that is the rate-limiting step in the manufacture of cholesterol. Statins reduce LDL-cholesterol, total cholesterol, and triglycerides and slightly increase high-density lipoprotein (HDL-c).
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