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USMLE Exam Prep

Category - Free USMLE Practice Test Questions

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Pepsinogen is an enzyme that, when released into the stomach, is activated by acid to form Pepsin. Pepsin is responsible for the hydrolysis of which substance?

Carbohydrates
Proteins
Lipids
All of the above

Explanation

Answer - B - Pepsin is responsible for the hydrolysis or break-down of proteins in the stomach into polypeptides and partially-digested proteinaceous foods. 99% of the pepsinogen that is released into the stomach stays there to activate pepsin. The remaining 1% gets absorbed and goes into the blood stream.

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