USMLE Exam Prep

Category - Free USMLE Practice Test Questions

Stevens-Johnson syndrome and TENs are variants of which disease?
  1. Aphthous ulcers
  2. Penphigus vulgaris
  3. Erythema multiforme
  4. Lichen Planus
Explanation
Answer: C - Stevens-Johnson syndrome and TENs are variants of erythema multiforme. The origins of the lesions are from sulfa drugs, vaccinations, and viral infections. These lesions primarily present on the face and extremities. Oral lesions present as vesicles and ulcerations and spread widely throughout the oral cavity. Stevens-Johnson syndrome is considered erythema multiforme miner. If it is severe, lesions display on skin, conjunctiva, genitalia, and oral mucosa, and triggered by drugs. Treatment includes systemic corticosteroids, acyclovir, and the discontinuation of causative drugs. TENs, the most severe form of erythema multiforme, must be treated in a burn unit.
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