Which one of the listed statements correctly describes the flow of blood in an individual with an atrial septal defect who develops Eisenmenger’s syndrome?
  1. Aorta to pulmonary artery to lungs to left atrium to left ventricle to aorta
  2. Left atrium to right atrium to right ventricle to lungs to left atrium
  3. Left ventricle to right ventricle to lungs to left atrium to right ventricle
  4. Right atrium to left atrium to left ventricle to aorta to right atrium
Explanation
Answer: D- Left-to-right congenital shunts are not initially cyanotic, but cyanosis may develop later (tardive cyanosis) if the shunt shifts to a right-to-left shunt due to increased pulmonary vascular resistance (Eisenmenger’s complex).
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