Calcium channel blockers act by antagonizing the L-type calcium channels in vascular smooth muscle. What are the effects on cardiac muscle?
  1. Increased cardiac muscle contractility, increased SA pacemaker rate, and increased atrioventricular conduction velocity in cardiac tissue
  2. Increased cardiac muscle contractility, increased SA pacemaker rate, and decreased atrioventricular conduction velocity in cardiac tissue
  3. Reduced cardiac muscle contractility, increased SA pacemaker rate, and increased atrioventricular conduction velocity in cardiac tissue
  4. Reduced cardiac muscle contractility, decreased SA pacemaker rate, and decreased atrioventricular conduction velocity in cardiac tissue
Explanation
Answer: D - Calcium channel blockers act by antagonizing L-type calcium channels in vascular smooth muscle, which leads to reduced cardiac muscle contractility, decreased SA pacemaker rate, and decreased atrioventricular conduction velocity in cardiac tissue.
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