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NAPLEX Pharmacy Exam Prep

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What is the mechanism of action of loratadine (Alavert/Claritin)?

  1. Loratadine is a 1st generation H-2 antagonist
  2. Loratadine is a 2nd generation H-1 agonist
  3. Loratadine is a 2nd generation H-1 antagonist
  4. Loratadine is a 1st generation dopamine-2 antagonist
Explanation

Answer - C - Loratadine is a 2nd generation H-1 antagonist and blocks the peripheral effects of histamine release.

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