Practice Quiz

INBDE Integrated National Board Dental Exam Prep Set 2

Category - NBDE II

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White sponge nevus is caused by a mutation of what gene:

  1. Keratin 4 and 13
  2. Keratin 5 and 12
  3. Keratin 1 and 49
  4. Keratin 21 and 23
Explanation

Answer: A - White sponge nevus is caused by a mutation of genes keratin 4 and keratin13. It is an autosomal dominate genetic disorder. The condition is also known as familial epithelial hyperplasia, or Cannon's disease. The mass is bilateral and rough due to epithelial thickening in the buccal mucosa. There is not treatment required.

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