Which of the following statements is TRUE of a Type IV hypersensitivity reaction?
  1. It is mediated by B cells
  2. It is an immediate response
  3. It involves the binding of class II MHC to a TCR
  4. An example of this reaction is seen with hemolytic anemia
Explanation
Answer: C - A Type IV hypersensitivity reaction involves the binding of a class II MHC to a TCR. It also involves the presentation of antigen by macrophage to T cells, thus producing tissue destruction.
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