Which of the following statements concerning ARDS is true?
  1. One of the causes of ARDS is CHF.
  2. Pulmonary capillary wedge pressure is elevated in ARDS.
  3. Surfactant production is reduced in ARDS.
  4. ARDS has a low mortality rate.
Explanation
Answer - C - Type II alveolar cells are damaged as part of the ARDS cascade, leading to a decrease in surfactant production and alveolar collapse. Risk factors for developing this non-cardiogenic pulmonary edema include aspiration of gastric contents, all types of shock, oxygen toxicity, fat embolism, major trauma, smoke inhalation, multiple blood transfusions, viral pneumonia, and burns. The PCWP is elevated in pulmonary edema caused by CHF, but is normal in pulmonary edema caused by ARDS since the edema is not caused by a deficient heart muscle. ARDS has a high mortality rate.
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