AP US History

Answer - B - After Christopher Columbus’s encounter with the Americas, the Native American population declined dramatically.
Key Takeaway: In the sixteenth century, the sudden arrival of Europeans in the New World caused immense devastation and destruction of the Native American population due to new diseases. The conquistadors of Spain brought smallpox with them to the New World, infecting native populations in order to gain control of the land. Later, Europeans also brought influenza, typhus, diphtheria, and measles to the New World.