Practice Quiz

FPGEE Foreign Pharmacy

Category - Pharmaceutical

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Which of the following may be used as an antidote to benzodiazepine overdose?

I. Flumazenil
II. Nalmefene
III. Physostigmine
IV. Protamine
  1. I only
  2. II only
  3. I, II and III only
  4. IV only
Explanation
Answer: A - Flumazenil is used as an antidote to benzodiazepine and acts as a competitive inhibitor at the GABA receptors. Nalmefene is a competitive antagonist at opioid receptors. Physostigmine is a classic acetylcholinesterase inhibitor and is used as an antidote for anticholinergics. Protamine is used to reverse the effects of heparin.
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