Practice Quiz

Podiatry and Medical - Set 2

Category - Podiatry Part II

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Which of the following is not a feature of Paget’s disease of the bone?
  1. Excessive bone resorption
  2. Alkaline phosphatase activityis decreased
  3. Patients can present with bone pain, fractures, deformity, and sensory deficits
  4. Bone is replaced by a soft, disorganized bone matrix with a mosaic pattern
Explanation
Answer − B − Alkaline phosphatase activity is not decreased in Paget’s disease of the bone. In Paget’s disease, the resorbed bone is replaced by a soft, disorganized bone matrix with a mosaic, rather than trabecular, pattern. Alkaline phosphatase activity is increased. Patients can present with bone pain, fractures, deformity, and sensory deficits.
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