FPGEE Foreign Pharmacy

Category - Pharmaceutical

Which of the following has a “Black Box Warning” associated with it?

I. Fluoxetine
II. Oxaprozin
III. Phenelzine
IV. Clopidogrel
  1. I and III only
  2. II and III only
  3. I, III, and IV only
  4. I, II, III, and IV
Explanation
Answer: D - All the drugs listed carry Black Box Warnings. Phenelzine and fluoxetine are both associated with increased suicidality (especially in adolescents). Oxaprozin has an increased risk of MI, stroke, thromboembolic, and adverse GI events. Clopidogrel carries a warning of decreased effectiveness in CYP2C19 poor metabolizers.
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