FPGEE Foreign Pharmacy

Category - Pharmaceutical

Which of the following excipients would be expected to decrease bioavailability?
  1. Starch
  2. Lactose
  3. Mannitol
  4. Magnesium stearate
Explanation
Answer: D - An excipient is an inactive substance used as a carrier for the active ingredients of a medication. Magnesium stearate is a lubricant and would tend to decrease solubility in water and therefore bioavailability. Starch, lactose, and mannitol would not be expected to decrease bioavailability.
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