Podiatry and Medical - Set 1

Answer − C − The drug that is considered a first-line agent in the chronic treatment of rheumatoid arthritis and in the treatment of choriocarcinoma is methotrexate. Methotrexate is an antimetabolite and antifolate drug that acts by inhibiting the creation of folic acid, a precursor for DNA. Methotrexate in very low dosages has proven effective in slowing the progression of rheumatoid arthritis and has low toxicity.