Practice Quiz

FPGEE Foreign Pharmacy

Category - Pharmaceutical

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Which of the following are alkylating agents?

I. Chlorambucil
II. Lomustine
III. Chloramphenicol
  1. I and II only
  2. None of the above
  3. I only
  4. II and III only
Explanation
Answer: A - Chlorambucil (a nitrogen mustard) and lomustine (a nitrosourea) are both alkylating agents and are used in CLL (Chlorambucil) and in primary/ metastatic brain tumors (Lomustine). Chloramphenicol is an anti-infective dichloroacetic acid derivative used in, for example, bacteremia, meningitis, or ocular infections.
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