The nurse is assigned to a 3-year-old, being treated with Chelation Therapy, and calcium disodium edetate due to poisoning. The nurse should carefully monitor for which of the following symptoms?

  1. Neurotoxicity
  2. Hepatomegaly
  3. Nephrotoxicity
  4. Ototoxicity
Explanation

Answer: C - Nephrotoxicity is a common side effect of calcium disodium edentate.

Nephrotoxicity, or kidney toxicity, is a potential side effect of calcium disodium edetate (also known as calcium disodium EDTA or calcium disodium versenate), which is a chelating agent used to treat heavy metal poisoning, such as lead poisoning. Chelating agents like calcium disodium edetate work by binding to heavy metal ions in the body and facilitating their excretion through urine.

Nephrotoxicity associated with calcium disodium edetate can occur because the chelating agent can have direct toxic effects on the kidneys, especially when used at high doses or for an extended period of time. Additionally, the kidneys are responsible for filtering and excreting the chelating agent along with the bound heavy metal ions, which can place additional stress on the renal system.

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