FPGEE Foreign Pharmacy

Category - Clinical

Thalidomide has historically been associated with teratogenesis. It is still used for some conditions. Which of the following conditions is thalidomide used for (on- or off-label)?
I. Bipolar disorder
II. HIV associated wasting syndrome
III. Erythema nodosum leprosum(ENL)
IV. Post-menopausal bleeding
  1. I and II only
  2. I and III only
  3. II and III only
  4. None of the above-thalidomide is never used.
Explanation
Answer: C − Thalidomide is an immunomodulator and an angiogenesis inhibitor. It is used on-label for ENL and off-label for HIV associated wasting syndrome. There is no rationale to use it for either bipolar disorder or post-menopausal bleeding.
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