Practice Quiz

NREMT Paramedic

Category - Cardiology

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Nitroglycerin causes vasodilatation to prevent the heart from acting like a reservoir of blood and to help it pump effectively. Why does sublingual administration of nitroglycerin work so well?
  1. The ducts in the tongue allow for fast absorption.
  2. The underside of the tongue is capillary rich.
  3. The large amount of saliva helps absorption.
  4. The drug gains access via tongue and gum line.
Explanation
Answer: B - Sublingual administration of nitroglycerin works so well due to the underside of the tongue being capillary rich. The capillaries act as a fast pathway for the drug to be effective quickly. Remember, how well a drug is absorbed is determined by concentration, pH, ionization, solubility, absorption surface, and blood flow rate through administration area.
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