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ADA NBDE National Board Dental Part I

Category - NBDE

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Measurement of the rate of creatinine clearance is used as a key determinant of renal function. In which of the following tissues is creatinine generated?

Adipose
Kidney
Liver
Skeletal muscle

Explanation

Answer: D - Although creatine is synthesized in the liver from guanidoacetate, which is produced in the kidneys, it is not used by these two tissues. Once synthesized, creatine is transported to cardiac and skeletal muscle, where it is phosphorylated and stored for future energy needs.

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ADA NBDE National Board Dental Part I

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ADA NBDE National Board Dental Part I

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