NREMT Advanced EMT

Category - Medical Knowledge

Free drug availability is highest in what patient?
  1. Teenagers
  2. Infants
  3. Toddlers
  4. Adults
Explanation
Answer - B - Free drug availability is highest in infants. Some drugs bind to plasma proteins in the blood. But not all the drug molecules bind. The ones that do not are available in the body to cause the desired or undesired effects. This is known as free drug availability. Infants (children under that age of one) have diminished plasma protein concentrations; these drugs have higher free drug availability. Because of this, you can expect to reach therapeutic and toxic effects at low doses.
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