Practice Quiz

CRNE Canadian Registered Nurse

Category - Wellness

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Darlene was admitted to the unit due to auditory hallucinations. A diagnosis of schizophrenia was made. The physician orders clozapine, an atypical antipsychotic medication. Before discharge, the nurse reminds the client about the possible adverse and serious effects of clozapine. The nurse emphasizes immediate medical treatment with the development of which of the following signs and symptoms?
  1. Orthostatic hypotension
  2. Polydipsia
  3. Sore throat
  4. Involuntary abnormal movements of the mouth
Explanation
Answer: C - Sore throat is a manifestation of agranulocytosis, an adverse effect of clozapine intake. Agranulocytosis, or insufficient granulocytes, increases the client’s risk for infection. Orthostatic hypotension is a common side effect of anti-depressants. Polydipsia is a side effect of lithium use. Involuntary abnormal movements are a side effect of long-term use of typical antipsychotics.
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