Podiatry and Medical - Set 1

Answer − D − Complications of high-dose glucocorticoid therapy include suppression of the hypothalamic-pituitary-adrenal axis (HPA). The HPA regulates many processes including reactions to stress, digestion, immune system, moods and emotions, sexuality, and energy storage and expenditure. Patients treated for longer than 2 weeks on high dose glucorticoid therapy need to be tapered off glucocorticoids slowly to avoid adrenal insufficiency.