Practice Quiz

FPGEE Foreign Pharmacy

Category - Pharmaceutical

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Clopidogrel is a common prescription drug. Which choice lists correct therapeutic class, mechanism of action, indications, dosage form, and adverse reactions?
  1. Antiplatelet agent, blocks binding of ADP to platelets, atherosclerosis, tablets, bleeding
  2. Platelet aggregation inhibitor, binds platelet-receptor glycoprotein and inhibits binding of fibrinogen, Acute coronary syndrome, intravenous, bleeding
  3. Antiplatelet agent, phosphodiesterase III inhibitor, tablet, intermittent claudication, no major adverse reactions
  4. Antiplatelet agent, unknown mechanism, thrombocytopenic purpura, pulmonary emboli
Explanation
Answer: A - Clopidogrel is marketed as Plavix and is an antiplatelet agent that inhibits platelet aggregation by blocking the binding of adenosine diphosphate (ADP) to platelets thereby blocking thrombus formation. It is indicated for patients with atherosclerosis and peripheral artery disease (PAD). Plavix comes as a 75mg tablet and a major adverse reaction is uncontrolled bleeding.
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