EPPP Psychology

Category - Biological Bases of Behavior

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Antipsychotics are one class of drug used to treat certain disorders, such as schizophrenia, brief psychotic disorder, and delusional disorder. As with any psychiatric drug, they have a range of side effects varying from mild to severe. Which of the following antipsychotics is associated with agranulocytosis (a sudden drop in the granulocyte count), which manifests as a sore throat and high fever?

Haldol
Clozaril
Stelazine
Prolixin

Explanation

Answer: B - Clozaril carries the risk of agranulocytosis, which is potentially lethal. For this reason, Clozaril is only administered when other antipsychotics have proven to be unsuccessful treatments.

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