Acetyl-CoA enhances the rate of gluconeogenesis by acting as an allosteric activator of which of the following enzymes?
  1. ACC
  2. PEP-carboxykinase
  3. pyruvate carboxylase
  4. PDH
Explanation
Answer: C - Acetyl-CoA enhances the rate of gluconeogenesis by acting as an allosteric activator of pyruvate carboxylase. The major substrates of gluconeogenesis are pyruvate and lactate.
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