Practice Quiz

Podiatry and Medical - Set 1

Category - Podiatry Part I

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ACE inhibitors (in addition to other effects) are known to exert which of the following responses?
  1. Decrease both ventricular preload and afterload
  2. Increase coronary perfusion
  3. Increase efficiency of oxygen extraction by cardiac and skeletal muscle
  4. Produce a positive inotropic effect and negative chronotropic effect
Explanation
Answer − A − ACE inhibitors decrease ventricular preload and afterload through the inhibition of ACE and the consequent decrease in production of the pressor peptide angiotensin II, along with prolongation of the actions of the vasodilator peptide bradykinin (which is normally degraded by ACE).
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