NCLEX-RN

Category - Pharmacological

A student nurse is preparing a drug study on several anti-malarial drugs. If a patient has systemic lupus erythematosus, which of the following antimalarial drugs may be ordered to relieve photosensitivity, rashes, joint pain and inflammation, hair loss, and malaise?
  1. Chloroquine
  2. Primaquine
  3. Hydroxychloroquine
  4. Mefloquine
Explanation
Answer: C - Hydroxychloroquine (Plaquenil) is an antimalarial drug that may be given to patients with SLE to relieve photosensitivity, rashes, arthritis, arthralgia, hair loss, and malaise. It would take 8-12 weeks of Plaquenil use before therapeutic effects were seen. Long term use of Plaquenil could result in blurred vision. Chloroquine is a drug of choice for malaria, but hydroxychloroquine is preferable because of its safety.
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