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FPGEE Foreign Pharmacy

Category - Pharmaceutical

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A patient is on lovastatin. What is the biochemical pathway that is inhibited by this drug?

The mevalonate pathway
The hexose monophosphate shunt
The eicosanoid pathway
The pentose phosphate pathway

Explanation

Answer: A - Lovastatin is an HMG-CoA reductase inhibitor. HMG-CoA reductase is the rate-limiting enzyme of the mevalonate (isoprenoid) pathway of cholesterol synthesis.

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