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FPGEE Foreign Pharmacy

Category - Clinical

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A patient is on cetirizine and paroxetine. Which of the following interactions between the two drugs is most likely?

Additive CNS effects
Decreased absorption of the cetirizine
Diminished CNS effects
None of the above - there are no interactions likely

Explanation

Answer: A − Cetirizine, a Histamine-1 receptor antagonist, is most likely to have additive CNS effects with paroxetine, an SSRI.

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