Practice Quiz

FPGEE Foreign Pharmacy

Category - Clinical

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A patient is diagnosed with an H. pylori associated ulcer. Which is generally the first-line treatment with such an ulcer?
  1. A proton pump inhibitor (PPI) plus antibiotics
  2. A proton pump inhibitor alone
  3. OTC NSAIDs
  4. Infliximab
Explanation
Answer: A - An H. pylori associated ulcer is treated with a PPI and antibiotics to decrease the acidity and eradicate the bacteria, respectively. The etiology of these ulcers indicates that a PPI alone is not an effective treatment. OTC NSAIDs are often the cause of ulcers and should be avoided. Infliximab is a TNF (Tumor Necrosis Factor) inhibitor and is used to treat GI inflammations (IBD) such as Crohn’s disease and ulcerative colitis (UC).
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