Practice Quiz

FPGEE Foreign Pharmacy

Category - Clinical

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A clinic specializing in congestive heart failure has a number of elderly patients and has asked you to monitor their outcomes. They have used both nesiritide and bosentan and would like your input on these drugs. You feel comfortable telling them:
  1. Nesiritide should not be used in patients with an obstructive cardiomyopathy. Bosentan may be used in these patients. Nesiritide should not be used in patients with a systolic pressure under 90mm Hg.
  2. Bosentan is an endothelin-receptor agonist and should be used cautiously in elderly patients with mitral stenosis.
  3. Both A and B are correct.
  4. B is correct, but A is incorrect. The systolic pressure may safely be less than 90mm Hg as long as the patient is continuously monitored.
Explanation
Answer: C - Both statements A and B are correct. Nesiritide is contraindicated in obstructive cardiomyopathy and in hypotensive patients with systolic pressures less than 90mm Hg. Bosentan should be used cautiously in patients with mitral stenosis.
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