CRNE Canadian Registered Nurse

Category - Wellness

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A client is prescribed clozapine (Clozaril). Which of the following laboratory studies should the nurse assess in order to monitor for the adverse effects of this medication?

Serum potassium
White blood cell count
Liver function test
Renal function test

Explanation

Answer: B - Clozapine may cause agranulocytosis, a condition where the white blood cell count drops below 3,000 cells/mm³; therefore a client taking clozapine should have his or her white blood cell count monitored. A reduced number of white blood cells greatly increases the client’s risk for infections. Clozapine intake is immediately stopped with the development of this adverse reaction.

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