Practice Quiz

NCLEX-RN

Category - Pharmacological

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A client diagnosed with multiple myeloma receives IV fluids and allopurinol (Zyloprim) before initiating chemotherapy. The purpose of these interventions is to reduce the risk of which complication of chemotherapy?
  1. Thrombocytopenia.
  2. Disseminated intravascular coagulation (DIC)
  3. Tumor lysis syndrome
  4. Infertility
Explanation
Answer: C - Tumor lysis syndrome occurs when a large number of cells are rapidly destroyed by chemotherapeutic drugs and released into the bloodstream. Untreated tumor lysis syndrome can result in hyperuricemia and acute renal failure. Allopurinol increases the excretion of purines to prevent these severe complications.
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