NCLEX-RN

Category - Pharmacological

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A client diagnosed with cancer is treated with busulfan (Myleran). The nurse should monitor the values of which of the following laboratory examinations?

Uric acid
BUN
Potassium
Clotting time

Explanation

Answer: A - Busulfan, a non-specific antineoplastic agent, disrupts the nucleic acid functions of cancer cells, preventing them from growing. Busulfan therapy stimulates rapid tumor cell lysis, which can result in excessive uric acid production. The nurse should, therefore, monitor the uric acid levels of the client who is under busulfan therapy. Untreated hyperuricemia causes renal stones and acute renal failure.

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