NAPLEX Pharmacy Exam Prep - Question List

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6. Which of the following chemical modifications would likely increase the water solubility of a drug?
  1. Conversion of an anhydrous form to a tri-hydrate
  2. Conversion from a crystalline to an amorphous form
  3. The addition of a lipophilic side group
  4. The removal of a hydroxyl group
7.

What is the mechanism of action of loratadine (Alavert/Claritin)?

  1. Loratadine is a 1st generation H-2 antagonist
  2. Loratadine is a 2nd generation H-1 agonist
  3. Loratadine is a 2nd generation H-1 antagonist
  4. Loratadine is a 1st generation dopamine-2 antagonist
8. Ipratropium is a _____ used to treat _____ and which rarely has the adverse effect of inducing ______.
  1. Bisphosphonate, osteopenia, tachycardia
  2. Bronchodilator/anti-cholinergic, COPD and asthma, arrythmias
  3. Bronchodilator/cholinergic agonist, COPD and asthma, arrythmias
  4. Serotonin antagonist, seizure disorders, tachycardia
9. Droperidol is used to treat ______ and is contraindicated with/in _____.
  1. Vertigo, orthostatic hypotension
  2. Perioperative nausea and vomiting, known or suspected increased QT interval
  3. Opioid withdrawal, muscle spasms
  4. Rheumatoid arthritis, known hypersensitivity
10. Which of the following are possible signs/symptoms/complications of lansoprazole?

I. GI hemorrhage.
II. Cerebrovascular accident.
III. Asthma.
IV. Myocardial infarction.
  1. All of the above
  2. None of the above
  3. I only
  4. I and III only

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