NAPLEX Pharmacy Exam Prep - Question List

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51. Ribavarin is a ____________ used to treat __________ that rarely has the adverse effect of inducing ____________.
  1. Serotonin antagonist, nausea and vomiting, paralysis
  2. Voltage-gated Na+ channel blocker, Parkinson’s disease, aplastic anemia
  3. Synthetic nucleoside analog, chronic hepatitis C, cardiac arrest
  4. HMG-CoA reductase inhibitor, hyperlipidemia, rhabdomyolysis
52. Which of the following is the brand name for rifabutin?
  1. Sandimmune
  2. Neoral
  3. Mycobutin
  4. Gengraf
53. Which of the following would be useful as an effective anti-androgen therapy in a 78-year-old patient with prostate cancer?

I. Bilateral orchiectomy.
II. A testosterone antagonist such as bicalutamide only.
III. An LH-RH antagonist such as cetrorelix.
  1. I only
  2. III only
  3. I and/or III
  4. II only
54. What is the mechanism of action of mycophenolate mofetil (CellCept)?
  1. Mycophenolate mofetil is a neurokinin-1 antagonist used to prevent chemotherapy-induced nausea and vomiting.
  2. Mycophenolate mofetil is a 5HT3 antagonist used to prevent post-operative nausea.
  3. Mycophenolate mofetil is a corticosteroid analog used as an immunosuppressant.
  4. Mycophenolate mofetil is an immunosuppressant used to prevent organ rejection.
55. Why is carbidopa added to levodopa for the treatment of Parkinson’s disease?
  1. It prevents degradation of levodopa in the periphery.
  2. It minimizes some of the side effects of levodopa used alone.
  3. Addition of carbidopa stabilizes levodopa by interfering with Phase III metabolism.
  4. Carbidopa complexes with levodopa to allow increased solubility.

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